Inhibition of NF-kappa B signaling restores responsiveness of castrate-resistant prostate cancer cells to anti-androgen treatment by decreasing androgen receptor-variant expression.

Jin R, Yamashita H, Yu X, Wang J, Franco OE, Wang Y, Hayward SW, Matusik RJ
Oncogene. 2015 34 (28): 3700-10

PMID: 25220414 · PMCID: PMC4362792 · DOI:10.1038/onc.2014.302

MeSH Terms (17)

Androgen Antagonists Anilides Antineoplastic Agents Antineoplastic Combined Chemotherapy Protocols Boronic Acids Bortezomib Cell Line, Tumor Humans Male NF-kappa B Nitriles Prostatic Neoplasms, Castration-Resistant Pyrazines Receptors, Androgen Signal Transduction Tosyl Compounds Xenograft Model Antitumor Assays

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