Sequence variation in CYP51A from the Y strain of Trypanosoma cruzi alters its sensitivity to inhibition.

Cherkesova TS, Hargrove TY, Vanrell MC, Ges I, Usanov SA, Romano PS, Lepesheva GI
FEBS Lett. 2014 588 (21): 3878-85

PMID: 25217832 · PMCID: PMC4252588 · DOI:10.1016/j.febslet.2014.08.030

MeSH Terms (13)

14-alpha Demethylase Inhibitors Amino Acid Sequence Amino Acid Substitution Animals Biocatalysis Chagas Disease Conserved Sequence Cytochrome P-450 Enzyme System Humans Models, Molecular Molecular Sequence Data Protein Conformation Trypanosoma cruzi

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