Short forms of Ste20-related proline/alanine-rich kinase (SPAK) in the kidney are created by aspartyl aminopeptidase (Dnpep)-mediated proteolytic cleavage.

Markadieu N, Rios K, Spiller BW, McDonald WH, Welling PA, Delpire E
J Biol Chem. 2014 289 (42): 29273-84

PMID: 25164821 · PMCID: PMC4200278 · DOI:10.1074/jbc.M114.604009

MeSH Terms (21)

Amino Acid Sequence Animals Blood Pressure Cloning, Molecular Glutamyl Aminopeptidase Humans Kidney Kidney Medulla Mass Spectrometry Metalloproteases Mice Mice, Inbred C57BL Molecular Sequence Data Oocytes Protein-Serine-Threonine Kinases Protein Binding Protein Structure, Secondary Recombinant Fusion Proteins Signal Transduction Sodium Xenopus laevis

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