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Targeting of splice variants of human cytochrome P450 2C8 (CYP2C8) to mitochondria and their role in arachidonic acid metabolism and respiratory dysfunction.

Bajpai P, Srinivasan S, Ghosh J, Nagy LD, Wei S, Guengerich FP, Avadhani NG
J Biol Chem. 2014 289 (43): 29614-30

PMID: 25160618 · PMCID: PMC4207977 · DOI:10.1074/jbc.M114.583062

MeSH Terms (27)

Alternative Splicing Amino Acids Amino Acid Sequence Animals Arachidonic Acid Aryl Hydrocarbon Hydroxylases Biocatalysis Cell Respiration Chlorocebus aethiops Computer Simulation COS Cells Cytochrome P-450 CYP2C8 Heme Hep G2 Cells Humans Isoenzymes Microsomes, Liver Mitochondria Models, Molecular Molecular Sequence Data Oxidation-Reduction Oxidative Stress Protein Binding Protein Transport Reactive Oxygen Species RNA, Messenger Sequence Alignment

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