Proprotein convertase subtilisin kexin type 9 promotes intestinal overproduction of triglyceride-rich apolipoprotein B lipoproteins through both low-density lipoprotein receptor-dependent and -independent mechanisms.

Rashid S, Tavori H, Brown PE, Linton MF, He J, Giunzioni I, Fazio S
Circulation. 2014 130 (5): 431-41

PMID: 25070550 · PMCID: PMC4115295 · DOI:10.1161/CIRCULATIONAHA.113.006720

MeSH Terms (18)

Animals Apolipoproteins B Caco-2 Cells Cell Survival Enterocytes Humans Hypertriglyceridemia Intestinal Mucosa Intestines Mice, Inbred C57BL Mice, Knockout Proprotein Convertase 9 Proprotein Convertases Receptors, LDL RNA, Small Interfering Serine Endopeptidases Transcription, Genetic Triglycerides

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