PET/CT with (124)I-cG250: great potential and some open questions.

Khandani AH, Rathmell WK, Wallen EM, Ivanovic M
AJR Am J Roentgenol. 2014 203 (2): 261-2

PMID: 25055257 · DOI:10.2214/AJR.14.12490

OBJECTIVE - A novel PET radiotracer, (124)I-cG250, is currently under clinical investigation to distinguish clear cell renal cell carcinoma from other benign and malignant renal masses. In this article, we will make suggestions on the data needed to maximize the use of this radiotracer.

CONCLUSION - Although the published data are promising, further data are needed to assess the potential usefulness of this agent when dealing with indeterminate renal masses.

MeSH Terms (11)

Antibodies, Monoclonal Carbonic Anhydrases Carcinoma, Renal Cell Humans Iodine Radioisotopes Kidney Neoplasms Multimodal Imaging Neoplasm Grading Positron-Emission Tomography Sensitivity and Specificity Tomography, X-Ray Computed

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