Repurposing the FDA-approved pinworm drug pyrvinium as a novel chemotherapeutic agent for intestinal polyposis.

Li B, Flaveny CA, Giambelli C, Fei DL, Han L, Hang BI, Bai F, Pei XH, Nose V, Burlingame O, Capobianco AJ, Orton D, Lee E, Robbins DJ
PLoS One. 2014 9 (7): e101969

PMID: 25003333 · PMCID: PMC4086981 · DOI:10.1371/journal.pone.0101969

MeSH Terms (13)

Adenomatous Polyposis Coli Animals Antineoplastic Agents Cell Survival Drug Approval Drug Repositioning Drug Screening Assays, Antitumor HCT116 Cells Humans Mice, Inbred C57BL Mice, Transgenic Pyrvinium Compounds Wnt Signaling Pathway

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