Time- and NADPH-dependent inhibition of cytochrome P450 3A4 by the cyclopentapeptide cilengitide: significance of the guanidine group and accompanying spectral changes.

Bojić M, Barbero L, Dolgos H, Freisleben A, Gallemann D, Riva S, Guengerich FP
Drug Metab Dispos. 2014 42 (9): 1438-46

PMID: 24985702 · DOI:10.1124/dmd.114.059295

MeSH Terms (12)

Adult Cytochrome P-450 CYP3A Enzyme Inhibitors Female Guanidine Heme Humans Male Microsomes, Liver NADP Oxidation-Reduction Snake Venoms

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