The fatty acid amide hydrolase inhibitor PF-3845 promotes neuronal survival, attenuates inflammation and improves functional recovery in mice with traumatic brain injury.

Tchantchou F, Tucker LB, Fu AH, Bluett RJ, McCabe JT, Patel S, Zhang Y
Neuropharmacology. 2014 85: 427-39

PMID: 24937045 · PMCID: PMC4437642 · DOI:10.1016/j.neuropharm.2014.06.006

MeSH Terms (20)

Amidohydrolases Animals Anxiety Brain Brain Injuries Caspase 3 Disease Models, Animal Extracellular Signal-Regulated MAP Kinases Male Memory Disorders Mice, Inbred C57BL Motor Activity Neuroimmunomodulation Neuroprotective Agents Piperidines Proto-Oncogene Proteins c-akt Pyridines Receptor, Cannabinoid, CB1 Receptor, Cannabinoid, CB2 Recovery of Function

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