Pancreatic β-cell-specific ablation of TASK-1 channels augments glucose-stimulated calcium entry and insulin secretion, improving glucose tolerance.

Dadi PK, Vierra NC, Jacobson DA
Endocrinology. 2014 155 (10): 3757-68

PMID: 24932805 · PMCID: PMC4164933 · DOI:10.1210/en.2013-2051

MeSH Terms (19)

Animals Calcium Calcium Signaling Cells, Cultured Female Glucose Glucose Intolerance Humans Insulin Insulin-Secreting Cells Insulin Secretion Male Membrane Potentials Mice Mice, Inbred C57BL Mice, Transgenic Nerve Tissue Proteins Organ Specificity Potassium Channels, Tandem Pore Domain

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