Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival.

Ă–zdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, Moses HL, Weaver VM, Maitra A, Allison JP, LeBleu VS, Kalluri R
Cancer Cell. 2014 25 (6): 719-34

PMID: 24856586 · PMCID: PMC4180632 · DOI:10.1016/j.ccr.2014.04.005

MeSH Terms (11)

Animals Carcinoma, Pancreatic Ductal Disease Models, Animal Fibroblasts Fibrosis Humans Immune Tolerance Mice Mice, Transgenic Pancreatic Neoplasms Survival Analysis

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