Differences in DNA methylation signatures reveal multiple pathways of progression from adenoma to colorectal cancer.

Luo Y, Wong CJ, Kaz AM, Dzieciatkowski S, Carter KT, Morris SM, Wang J, Willis JE, Makar KW, Ulrich CM, Lutterbaugh JD, Shrubsole MJ, Zheng W, Markowitz SD, Grady WM
Gastroenterology. 2014 147 (2): 418-29.e8

PMID: 24793120 · PMCID: PMC4107146 · DOI:10.1053/j.gastro.2014.04.039

MeSH Terms (23)

Adenoma Aged Case-Control Studies Cell Transformation, Neoplastic Cluster Analysis Colorectal Neoplasms CpG Islands Disease Progression DNA Methylation DNA Mutational Analysis Epigenesis, Genetic Gene Expression Profiling Gene Expression Regulation, Neoplastic Genetic Predisposition to Disease Genome-Wide Association Study Humans Middle Aged Mutation Oligonucleotide Array Sequence Analysis Phenotype Proto-Oncogene Proteins Proto-Oncogene Proteins p21(ras) ras Proteins

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