Secondary metabolism pathway polymorphisms and plasma efavirenz concentrations in HIV-infected adults with CYP2B6 slow metabolizer genotypes.

Haas DW, Kwara A, Richardson DM, Baker P, Papageorgiou I, Acosta EP, Morse GD, Court MH
J Antimicrob Chemother. 2014 69 (8): 2175-82

PMID: 24729586 · PMCID: PMC4100708 · DOI:10.1093/jac/dku110

MeSH Terms (21)

Adult African Continental Ancestry Group Alkynes Anti-HIV Agents Benzoxazines Cyclopropanes Cytochrome P-450 CYP2A6 Cytochrome P-450 CYP2B6 Cytochrome P-450 CYP2B6 Inducers European Continental Ancestry Group Female Gene Dosage Glucuronosyltransferase HIV-1 HIV Infections Humans Male Polymorphism, Single Nucleotide Prospective Studies Reverse Transcriptase Inhibitors Secondary Metabolism

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