Pro32Pro33 mutations in the integrin β3 PSI domain result in αIIbβ3 priming and enhanced adhesion: reversal of the hypercoagulability phenotype by the Src inhibitor SKI-606.

Oliver KH, Jessen T, Crawford EL, Chung CY, Sutcliffe JS, Carneiro AM
Mol Pharmacol. 2014 85 (6): 921-31

PMID: 24695082 · PMCID: PMC4014669 · DOI:10.1124/mol.114.091736

MeSH Terms (20)

Amino Acid Sequence Aniline Compounds Animals Base Sequence Cell Adhesion DNA Primers Humans Integrin beta3 Mice Molecular Sequence Data Mutation Nitriles Phenotype Platelet Glycoprotein GPIIb-IIIa Complex Polymerase Chain Reaction Proline Quinolines Sequence Homology, Amino Acid src-Family Kinases Thrombophilia

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