Mislocalization of the cell polarity protein scribble promotes mammary tumorigenesis and is associated with basal breast cancer.

Feigin ME, Akshinthala SD, Araki K, Rosenberg AZ, Muthuswamy LB, Martin B, Lehmann BD, Berman HK, Pietenpol JA, Cardiff RD, Muthuswamy SK
Cancer Res. 2014 74 (11): 3180-94

PMID: 24662921 · PMCID: PMC4096808 · DOI:10.1158/0008-5472.CAN-13-3415

MeSH Terms (20)

Animals Breast Neoplasms Carcinogenesis Cell Line Cell Line, Tumor Cell Polarity Class I Phosphatidylinositol 3-Kinases Female Gene Expression HEK293 Cells Humans Membrane Proteins Mice Mice, Transgenic Phosphatidylinositol 3-Kinases Proto-Oncogene Proteins c-akt PTEN Phosphohydrolase Signal Transduction TOR Serine-Threonine Kinases Tumor Suppressor Proteins

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