Incidence of hypercoagulable events after image-guided percutaneous cryoablation of renal tumors: a single-center experience.

Hartman JB, Bhojwani N, Corn DJ, Cooney MM, Haaga J, Ponsky L, Abouassaly R, Paspulati A, Prologo JD
J Vasc Interv Radiol. 2014 25 (5): 776-9

PMID: 24656177 · PMCID: PMC3995864 · DOI:10.1016/j.jvir.2014.01.027

PURPOSE - To identify retrospectively hypercoagulable events that occurred over time in patients who underwent image-guided percutaneous renal cryoablation and compare the incidence with a cohort of patients who underwent surgical partial nephrectomy (PN) during the same time period.

MATERIALS AND METHODS - An electronic medical record database was queried for patients who underwent percutaneous image-guided renal mass cryoablation or PN between September 2006 and June 2012. Records were examined for thrombotic events during the year following the procedure in each group. Incidence rates, Kaplan-Meier estimates, and patient demographic variables were compared using the stratified log-rank test and t test for independent samples.

RESULTS - The study comprised 114 cryoablation cases. The cumulative incidence of thrombotic events after 1 year was 4.39%. The incidence per 100 person-years was 4.84. There were 105 PN cases. The cumulative incidence of thrombotic events after 1 year was 1.0%. The incidence per 100 person-years was 1.14. The person-time incidence rate difference for these two groups did not reach statistical significance (P = .0894).

CONCLUSIONS - The incidence of thrombotic events in patients who underwent percutaneous renal cryoablation in this study was not significantly different than a comparable cohort who underwent surgical PN during the same time period.

Copyright © 2014 SIR. Published by Elsevier Inc. All rights reserved.

MeSH Terms (21)

Adult Aged Aged, 80 and over Causality Comorbidity Cryosurgery Female Humans Incidence Kidney Neoplasms Male Middle Aged Nephrectomy Ohio Postoperative Complications Retrospective Studies Risk Factors Surgery, Computer-Assisted Thrombosis Tomography, X-Ray Computed Treatment Outcome

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