Obesity-associated variants within FTO form long-range functional connections with IRX3.

Smemo S, Tena JJ, Kim KH, Gamazon ER, Sakabe NJ, Gómez-Marín C, Aneas I, Credidio FL, Sobreira DR, Wasserman NF, Lee JH, Puviindran V, Tam D, Shen M, Son JE, Vakili NA, Sung HK, Naranjo S, Acemel RD, Manzanares M, Nagy A, Cox NJ, Hui CC, Gomez-Skarmeta JL, Nóbrega MA
Nature. 2014 507 (7492): 371-5

PMID: 24646999 · PMCID: PMC4113484 · DOI:10.1038/nature13138

MeSH Terms (26)

Adipose Tissue Alpha-Ketoglutarate-Dependent Dioxygenase FTO Animals Basal Metabolism Body Mass Index Body Weight Brain Diabetes Mellitus, Type 2 Diet Genes, Dominant Homeodomain Proteins Humans Hypothalamus Introns Male Mice Mixed Function Oxygenases Obesity Oxo-Acid-Lyases Phenotype Polymorphism, Single Nucleotide Promoter Regions, Genetic Proteins Thinness Transcription Factors Zebrafish

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