Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator.

Wu H, Wang C, Gregory KJ, Han GW, Cho HP, Xia Y, Niswender CM, Katritch V, Meiler J, Cherezov V, Conn PJ, Stevens RC
Science. 2014 344 (6179): 58-64

PMID: 24603153 · PMCID: PMC3991565 · DOI:10.1126/science.1249489

MeSH Terms (20)

Allosteric Regulation Allosteric Site Amino Acid Sequence Benzamides Binding Sites Cholesterol Crystallography, X-Ray Humans Hydrophobic and Hydrophilic Interactions Ligands Models, Molecular Molecular Sequence Data Mutation Protein Conformation Protein Multimerization Protein Structure, Secondary Protein Structure, Tertiary Receptors, Metabotropic Glutamate Structure-Activity Relationship Thiazoles

Connections (4)

This publication is referenced by other Labnodes entities:

Links