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Race, regionality and pre-diabetes in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study.

Lee LT, Alexandrov AW, Howard VJ, Kabagambe EK, Hess MA, McLain RM, Safford MM, Howard G
Prev Med. 2014 63: 43-7

PMID: 24594101 · PMCID: PMC4621076 · DOI:10.1016/j.ypmed.2014.02.013

OBJECTIVE - To determine the association between race, region and pre-diabetes.

METHOD - The study used 2003-2007 United States baseline data from the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study for this cross-sectional analysis. Participants in this study were 45years or older at recruitment. Logistic regression was used to assess whether race and region are associated with pre-diabetes independent of demographics, socioeconomic factors and risk factors.

RESULTS - Twenty-four percent of the study participants (n=19,889) had pre-diabetes. The odds ratio (95% confidence interval) for having pre-diabetes was 1.28 (1.19-1.36) for blacks relative to whites and 1.18 (1.10-1.26) for people living in the Stroke Belt region relative to the other parts of the United States. The odds of having pre-diabetes for Stroke Belt participants changed minimally after additional adjustment for race (OR=1.20; 1.13-1.28), age and sex (OR=1.24; 1.16-1.32), socioeconomic status (OR=1.22; 1.15-1.31) and risk factors (OR=1.26; 1.17-1.35). In the adjusted model, being black was independently associated with pre-diabetes (OR=1.19; 1.10-1.28).

CONCLUSION - The prevalence of pre-diabetes was higher for both blacks and whites living in the Stroke Belt relative to living outside the Stroke Belt, and the prevalence of pre-diabetes was higher for blacks independent of region.

Copyright © 2014 Elsevier Inc. All rights reserved.

MeSH Terms (18)

African Americans Aged Aged, 80 and over Age Factors Cross-Sectional Studies Cultural Characteristics European Continental Ancestry Group Female Humans Male Middle Aged Prediabetic State Prevalence Risk Factors Sex Factors Socioeconomic Factors Southeastern United States Stroke

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