The p75 neurotrophin receptor evades the endolysosomal route in neuronal cells, favouring multivesicular bodies specialised for exosomal release.

Escudero CA, Lazo OM, Galleguillos C, Parraguez JI, Lopez-Verrilli MA, Cabeza C, Leon L, Saeed U, Retamal C, Gonzalez A, Marzolo MP, Carter BD, Court FA, Bronfman FC
J Cell Sci. 2014 127 (Pt 9): 1966-79

PMID: 24569882 · PMCID: PMC4004974 · DOI:10.1242/jcs.141754

MeSH Terms (13)

Animals Endosomes Exosomes Lysosomes Microscopy, Fluorescence Multivesicular Bodies Nerve Tissue Proteins Neurons PC12 Cells Rats Receptors, Growth Factor Receptors, Nerve Growth Factor RNA Interference

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