Oncogenic and sorafenib-sensitive ARAF mutations in lung adenocarcinoma.

Imielinski M, Greulich H, Kaplan B, Araujo L, Amann J, Horn L, Schiller J, Villalona-Calero MA, Meyerson M, Carbone DP
J Clin Invest. 2014 124 (4): 1582-6

PMID: 24569458 · PMCID: PMC3973082 · DOI:10.1172/JCI72763

MeSH Terms (19)

Adenocarcinoma Adenocarcinoma of Lung Aged Amino Acid Substitution Antineoplastic Agents Cell Transformation, Neoplastic DNA, Neoplasm Female Humans Lung Neoplasms Molecular Targeted Therapy Mutation, Missense Niacinamide Oncogenes Phenylurea Compounds Proto-Oncogene Proteins A-raf Proto-Oncogene Proteins B-raf Proto-Oncogene Proteins c-raf Sorafenib

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