A genetic atlas of human admixture history.

Hellenthal G, Busby GBJ, Band G, Wilson JF, Capelli C, Falush D, Myers S
Science. 2014 343 (6172): 747-751

PMID: 24531965 · PMCID: PMC4209567 · DOI:10.1126/science.1243518

Modern genetic data combined with appropriate statistical methods have the potential to contribute substantially to our understanding of human history. We have developed an approach that exploits the genomic structure of admixed populations to date and characterize historical mixture events at fine scales. We used this to produce an atlas of worldwide human admixture history, constructed by using genetic data alone and encompassing over 100 events occurring over the past 4000 years. We identified events whose dates and participants suggest they describe genetic impacts of the Mongol empire, Arab slave trade, Bantu expansion, first millennium CE migrations in Eastern Europe, and European colonialism, as well as unrecorded events, revealing admixture to be an almost universal force shaping human populations.

MeSH Terms (17)

Alleles Chromosome Painting Computer Simulation DNA Europe, Eastern Genetic Drift Genotyping Techniques Haplotypes History, Ancient Human Migration Humans Middle East Models, Genetic Mongolia Polymorphism, Single Nucleotide Population Software

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