Identification of specific ligand-receptor interactions that govern binding and cooperativity of diverse modulators to a common metabotropic glutamate receptor 5 allosteric site.

Gregory KJ, Nguyen ED, Malosh C, Mendenhall JL, Zic JZ, Bates BS, Noetzel MJ, Squire EF, Turner EM, Rook JM, Emmitte KA, Stauffer SR, Lindsley CW, Meiler J, Conn PJ
ACS Chem Neurosci. 2014 5 (4): 282-95

PMID: 24528109 · PMCID: PMC3990945 · DOI:10.1021/cn400225x

MeSH Terms (8)

Binding Sites Computer Simulation Molecular Docking Simulation Mutagenesis, Site-Directed Protein Binding Protein Interaction Mapping Receptor, Metabotropic Glutamate 5 Structure-Activity Relationship

Connections (4)

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