Axonal transport of TDP-43 mRNA granules is impaired by ALS-causing mutations.

Alami NH, Smith RB, Carrasco MA, Williams LA, Winborn CS, Han SSW, Kiskinis E, Winborn B, Freibaum BD, Kanagaraj A, Clare AJ, Badders NM, Bilican B, Chaum E, Chandran S, Shaw CE, Eggan KC, Maniatis T, Taylor JP
Neuron. 2014 81 (3): 536-543

PMID: 24507191 · PMCID: PMC3939050 · DOI:10.1016/j.neuron.2013.12.018

MeSH Terms (20)

Amyotrophic Lateral Sclerosis Animals Animals, Genetically Modified Axonal Transport Cells, Cultured Cerebral Cortex DNA-Binding Proteins Drosophila Drosophila Proteins Humans Kruppel-Like Transcription Factors Luminescent Proteins Mice Mitochondria Motor Neurons Mutation Octamer Transcription Factor-3 RNA, Messenger RNA-Binding Proteins SOXB1 Transcription Factors

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