The leukotriene B₄/BLT₁ axis is a key determinant in susceptibility and resistance to histoplasmosis.

Secatto A, Soares EM, Locachevic GA, Assis PA, Paula-Silva FW, Serezani CH, de Medeiros AI, Faccioli LH
PLoS One. 2014 9 (1): e85083

PMID: 24465479 · PMCID: PMC3897419 · DOI:10.1371/journal.pone.0085083

MeSH Terms (20)

Animals Arachidonate 5-Lipoxygenase Disease Susceptibility Enzyme Inhibitors Gene Expression Histoplasma Histoplasmosis Host-Pathogen Interactions Host Specificity Leukotriene B4 Lung Macrophages Mice Mice, 129 Strain Mice, Inbred C57BL Phagocytosis Receptors, Leukotriene B4 Rodent Diseases Signal Transduction Spleen

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