Antipsychotic drug-like effects of the selective M4 muscarinic acetylcholine receptor positive allosteric modulator VU0152100.

Byun NE, Grannan M, Bubser M, Barry RL, Thompson A, Rosanelli J, Gowrishankar R, Kelm ND, Damon S, Bridges TM, Melancon BJ, Tarr JC, Brogan JT, Avison MJ, Deutch AY, Wess J, Wood MR, Lindsley CW, Gore JC, Conn PJ, Jones CK
Neuropsychopharmacology. 2014 39 (7): 1578-93

PMID: 24442096 · PMCID: PMC4023154 · DOI:10.1038/npp.2014.2

MeSH Terms (25)

Amphetamine Animals Antipsychotic Agents Blood Pressure Brain Cell Line, Transformed Central Nervous System Stimulants Disease Models, Animal Dopamine Plasma Membrane Transport Proteins Fear Heart Rate Humans Hyperkinesis Male Mice Mice, Inbred C57BL Mice, Knockout Motor Activity Protein Binding Pyridines Rats Rats, Sprague-Dawley Receptor, Muscarinic M4 Reflex, Startle Thiophenes

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