A potent anti-dengue human antibody preferentially recognizes the conformation of E protein monomers assembled on the virus surface.

Fibriansah G, Tan JL, Smith SA, de Alwis AR, Ng TS, Kostyuchenko VA, Ibarra KD, Wang J, Harris E, de Silva A, Crowe JE, Lok SM
EMBO Mol Med. 2014 6 (3): 358-71

PMID: 24421336 · PMCID: PMC3958310 · DOI:10.1002/emmm.201303404

MeSH Terms (17)

Amino Acid Sequence Animals Antibodies, Monoclonal Antibodies, Neutralizing Antibodies, Viral Cell Line Dengue Dengue Virus Epitopes Humans Immunoglobulin Fab Fragments Mice Molecular Dynamics Simulation Molecular Sequence Data Protein Structure, Tertiary Viral Envelope Proteins Virus Internalization

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