Single-center experience and long-term outcomes of duct-to-duct biliary reconstruction in infantile living donor liver transplantation.

Yamamoto H, Hayashida S, Asonuma K, Honda M, Suda H, Murokawa T, Ohya Y, Lee KJ, Takeichi T, Inomata Y
Liver Transpl. 2014 20 (3): 347-54

PMID: 24415519 · DOI:10.1002/lt.23819

The indications for duct-to-duct (DD) biliary reconstruction in living donor liver transplantation (LDLT) for small children are still controversial. In this study, the feasibility of DD biliary reconstruction versus Roux-en-Y (RY) biliary reconstruction was investigated in terms of long-term outcomes. Fifty-six children who consecutively underwent LDLT with a weight less than or equal to 10.0 kg were enrolled. Biliary reconstruction was performed in a DD fashion for 20 patients and in an RY fashion for 36 patients. During a minimum follow-up of 2 years, the incidence of biliary strictures was 5.0% in the DD group and 11.1% in the RY group. Cholangitis during the posttransplant period was observed in the RY group only. There were no deaths related to biliary problems. This study shows that DD reconstruction in LDLT for small children (weighing 10.0 kg or less) is a feasible option for biliary reconstruction.

© 2014 American Association for the Study of Liver Diseases.

MeSH Terms (16)

Anastomosis, Roux-en-Y Bile Ducts Body Weight Child, Preschool Cholangiography Cholangitis Cholestasis End Stage Liver Disease Female Follow-Up Studies Humans Infant Liver Transplantation Living Donors Male Treatment Outcome

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