High-resolution structures and orientations of antimicrobial peptides piscidin 1 and piscidin 3 in fluid bilayers reveal tilting, kinking, and bilayer immersion.

Perrin BS, Tian Y, Fu R, Grant CV, Chekmenev EY, Wieczorek WE, Dao AE, Hayden RM, Burzynski CM, Venable RM, Sharma M, Opella SJ, Pastor RW, Cotten ML
J Am Chem Soc. 2014 136 (9): 3491-504

PMID: 24410116 · PMCID: PMC3985945 · DOI:10.1021/ja411119m

MeSH Terms (10)

Antimicrobial Cationic Peptides Fish Proteins Hydrophobic and Hydrophilic Interactions Immersion Lipid Bilayers Liquid Crystals Molecular Dynamics Simulation Phosphatidylcholines Phosphatidylglycerols Protein Structure, Secondary

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