5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) effect on glucose production, but not energy metabolism, is independent of hepatic AMPK in vivo.

Hasenour CM, Ridley DE, Hughey CC, James FD, Donahue EP, Shearer J, Viollet B, Foretz M, Wasserman DH
J Biol Chem. 2014 289 (9): 5950-9

PMID: 24403081 · PMCID: PMC3937663 · DOI:10.1074/jbc.M113.528232

MeSH Terms (14)

Aminoimidazole Carboxamide AMP-Activated Protein Kinases Animals Energy Metabolism Fatty Acids Glucose Hypoglycemic Agents Liver Mice Mice, Knockout Mitochondria, Liver Oxidative Phosphorylation Ribonucleotides Triglycerides

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