Neuroprotective targets through which 6-acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79), a sigma receptor ligand, mitigates the effects of methamphetamine in vitro.

Kaushal N, Robson MJ, Rosen A, McCurdy CR, Matsumoto RR
Eur J Pharmacol. 2014 724: 193-203

PMID: 24380829 · PMCID: PMC3993961 · DOI:10.1016/j.ejphar.2013.12.039

MeSH Terms (16)

Animals Apoptosis Benzoxazoles Caspases Cell Line, Tumor eIF-2 Kinase Fever Ligands Methamphetamine Mice Necrosis Neuroprotective Agents Piperazines Reactive Nitrogen Species Reactive Oxygen Species Receptors, sigma

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