BRAF fusions define a distinct molecular subset of melanomas with potential sensitivity to MEK inhibition.

Hutchinson KE, Lipson D, Stephens PJ, Otto G, Lehmann BD, Lyle PL, Vnencak-Jones CL, Ross JS, Pietenpol JA, Sosman JA, Puzanov I, Miller VA, Pao W
Clin Cancer Res. 2013 19 (24): 6696-702

PMID: 24345920 · PMCID: PMC3880773 · DOI:10.1158/1078-0432.CCR-13-1746

MeSH Terms (16)

Adult Cell Line, Tumor Female High-Throughput Nucleotide Sequencing Humans Male MAP Kinase Signaling System Melanoma Mitogen-Activated Protein Kinase Kinases Multienzyme Complexes Mutation Oncogene Proteins, Fusion Protein Kinase Inhibitors Proto-Oncogene Proteins B-raf Skin Neoplasms Sulfate Adenylyltransferase

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