PPARĪ± activation can help prevent and treat non-small cell lung cancer.

Skrypnyk N, Chen X, Hu W, Su Y, Mont S, Yang S, Gangadhariah M, Wei S, Falck JR, Jat JL, Zent R, Capdevila JH, Pozzi A
Cancer Res. 2014 74 (2): 621-31

PMID: 24302581 · PMCID: PMC3902646 · DOI:10.1158/0008-5472.CAN-13-1928

MeSH Terms (21)

Animals Arachidonic Acids Bezafibrate Carcinoma, Non-Small-Cell Lung Cell Line, Tumor Cell Proliferation Cytochrome P-450 Enzyme System Cytochrome P450 Family 2 Disease Models, Animal Endothelial Cells Female Gene Expression Regulation, Neoplastic Humans Lung Neoplasms Male Mice Neoplasm Metastasis Neoplasm Transplantation Neovascularization, Pathologic PPAR alpha Pyrimidines

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