Targeting Plasmodium PI(4)K to eliminate malaria.

McNamara CW, Lee MC, Lim CS, Lim SH, Roland J, Simon O, Yeung BK, Chatterjee AK, McCormack SL, Manary MJ, Zeeman AM, Dechering KJ, Kumar TS, Henrich PP, Gagaring K, Ibanez M, Kato N, Kuhen KL, Fischli C, Nagle A, Rottmann M, Plouffe DM, Bursulaya B, Meister S, Rameh L, Trappe J, Haasen D, Timmerman M, Sauerwein RW, Suwanarusk R, Russell B, Renia L, Nosten F, Tully DC, Kocken CH, Glynne RJ, Bodenreider C, Fidock DA, Diagana TT, Winzeler EA
Nature. 2013 504 (7479): 248-253

PMID: 24284631 · PMCID: PMC3940870 · DOI:10.1038/nature12782

MeSH Terms (24)

1-Phosphatidylinositol 4-Kinase Adenosine Triphosphate Animals Binding Sites Cytokinesis Drug Resistance Fatty Acids Female Hepatocytes Humans Imidazoles Life Cycle Stages Macaca mulatta Malaria Male Models, Biological Models, Molecular Phosphatidylinositol Phosphates Plasmodium Pyrazoles Quinoxalines rab GTP-Binding Proteins Reproducibility of Results Schizonts

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