Genome wide analysis of drug-induced torsades de pointes: lack of common variants with large effect sizes.

Behr ER, Ritchie MD, Tanaka T, Kääb S, Crawford DC, Nicoletti P, Floratos A, Sinner MF, Kannankeril PJ, Wilde AA, Bezzina CR, Schulze-Bahr E, Zumhagen S, Guicheney P, Bishopric NH, Marshall V, Shakir S, Dalageorgou C, Bevan S, Jamshidi Y, Bastiaenen R, Myerburg RJ, Schott JJ, Camm AJ, Steinbeck G, Norris K, Altman RB, Tatonetti NP, Jeffery S, Kubo M, Nakamura Y, Shen Y, George AL, Roden DM
PLoS One. 2013 8 (11): e78511

PMID: 24223155 · PMCID: PMC3819377 · DOI:10.1371/journal.pone.0078511

MeSH Terms (21)

Adolescent Adult Aged Aged, 80 and over Alleles Anti-Arrhythmia Agents Arrhythmias, Cardiac Child European Continental Ancestry Group Female Gene Frequency Genetic Loci Genetic Predisposition to Disease Genome, Human Genome-Wide Association Study Humans Male Middle Aged Odds Ratio Polymorphism, Single Nucleotide Torsades de Pointes

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