Calsequestrin 2 deletion causes sinoatrial node dysfunction and atrial arrhythmias associated with altered sarcoplasmic reticulum calcium cycling and degenerative fibrosis within the mouse atrial pacemaker complex1.

Glukhov AV, Kalyanasundaram A, Lou Q, Hage LT, Hansen BJ, Belevych AE, Mohler PJ, Knollmann BC, Periasamy M, Gy├Ârke S, Fedorov VV
Eur Heart J. 2015 36 (11): 686-97

PMID: 24216388 · PMCID: PMC4359358 · DOI:10.1093/eurheartj/eht452

MeSH Terms (14)

Action Potentials Animals Atrial Fibrillation Atrial Function Bradycardia Calcium Calsequestrin Cardiomegaly Fibrosis Gene Deletion Gene Knockout Techniques Mice, Transgenic Sarcoplasmic Reticulum Sinoatrial Node

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