Direct monitoring of the strand passage reaction of DNA topoisomerase II triggers checkpoint activation.

Furniss KL, Tsai HJ, Byl JA, Lane AB, Vas AC, Hsu WS, Osheroff N, Clarke DJ
PLoS Genet. 2013 9 (10): e1003832

PMID: 24098144 · PMCID: PMC3789831 · DOI:10.1371/journal.pgen.1003832

MeSH Terms (12)

Cell Cycle Cell Cycle Checkpoints Cell Cycle Proteins Checkpoint Kinase 2 Chromosome Segregation DNA DNA Topoisomerases, Type II Humans Kinetochores Mad2 Proteins Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins

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