Mitochondrial glutathione depletion reveals a novel role for the pyruvate dehydrogenase complex as a key H2O2-emitting source under conditions of nutrient overload.

Fisher-Wellman KH, Gilliam LAA, Lin CT, Cathey BL, Lark DS, Darrell Neufer P
Free Radic Biol Med. 2013 65: 1201-1208

PMID: 24056031 · PMCID: PMC3965186 · DOI:10.1016/j.freeradbiomed.2013.09.008

MeSH Terms (17)

Adult Animals Female Glutathione Humans Hydrogen Peroxide Male Mice Mice, Inbred C57BL Mitochondria, Muscle NAD Oxidation-Reduction Pyruvate Dehydrogenase Complex Rats Rats, Sprague-Dawley Respiration Superoxides

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