A liver Hif-2α-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition.

Wei K, Piecewicz SM, McGinnis LM, Taniguchi CM, Wiegand SJ, Anderson K, Chan CW, Mulligan KX, Kuo D, Yuan J, Vallon M, Morton L, Lefai E, Simon MC, Maher JJ, Mithieux G, Rajas F, Annes J, McGuinness OP, Thurston G, Giaccia AJ, Kuo CJ
Nat Med. 2013 19 (10): 1331-1337

PMID: 24037094 · PMCID: PMC3795838 · DOI:10.1038/nm.3295

MeSH Terms (11)

Animals Basic Helix-Loop-Helix Transcription Factors Diabetes Mellitus, Type 2 Insulin Insulin Receptor Substrate Proteins Liver Mice Mice, Inbred C57BL Polymerase Chain Reaction Signal Transduction Vascular Endothelial Growth Factor A

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