Insulin growth factor signaling is regulated by microRNA-486, an underexpressed microRNA in lung cancer.

Peng Y, Dai Y, Hitchcock C, Yang X, Kassis ES, Liu L, Luo Z, Sun HL, Cui R, Wei H, Kim T, Lee TJ, Jeon YJ, Nuovo GJ, Volinia S, He Q, Yu J, Nana-Sinkam P, Croce CM
Proc Natl Acad Sci U S A. 2013 110 (37): 15043-8

PMID: 23980150 · PMCID: PMC3773758 · DOI:10.1073/pnas.1307107110

MeSH Terms (22)

3' Untranslated Regions Animals Apoptosis Carcinoma, Non-Small-Cell Lung Cell Cycle Checkpoints Cell Line, Tumor Cell Movement Cell Proliferation Class Ia Phosphatidylinositol 3-Kinase Gene Expression Regulation, Neoplastic Genes, p53 Genes, Tumor Suppressor Humans Insulin-Like Growth Factor I Lung Neoplasms Mice Mice, Nude MicroRNAs Phosphoinositide-3 Kinase Inhibitors Receptor, IGF Type 1 RNA, Small Interfering Signal Transduction

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