Severe obesity is associated with 3-fold higher radiation dose rate during ureteroscopy.

Hsi RS, Zamora DA, Kanal KM, Harper JD
Urology. 2013 82 (4): 780-5

PMID: 23958504 · PMCID: PMC4843513 · DOI:10.1016/j.urology.2013.06.030

OBJECTIVE - To investigate and characterize the association between fluoroscopy radiation dose rate and various patient size metrics during ureteroscopy.

MATERIALS AND METHODS - Fluoroscopy data were collected from 100 patients undergoing ureteroscopy for stone disease. Radiation dose rates were determined from fluoroscopy dose and time. Estimated entrance skin dose was calculated from air kerma (AK) by applying correction factors. Effective dose (ED) was estimated with Monte Carlo-based simulation software. Patient size metrics included body mass index (BMI), anterior-posterior (AP) midline distance, AP transrenal thickness, and region of interest (ROI) pixel value magnitude on computed tomography scout. Univariate and multivariate regression analyses were performed to determine the association between AK dose rate and patient size metrics, adjusting for laterality and stone location.

RESULTS - Obese patients (>30 kg/m(2)) comprised 46% of the cohort. Mean fluoroscopy time, displayed AK, entrance skin dose, and ED were 4.2 ± 6.0 second, 1.2 ± 2.1 mGy, 1.2 ± 2.2 mGy, and 0.08 ± 0.15 mSv, respectively. Mean AK dose rate and ED dose rates were 0.30 ± 0.23 mGy/second and 0.021 ± 0.016 mSv/second, respectively. Compared with the nonobese category, the highest BMI category (≥35 kg/m(2)) had over a 3-fold higher mean AK rate (0.50 vs 0.16 mGy/second). On univariate and multivariate analysis, BMI, AP midline distance, AP transrenal thickness, and computed tomography scout region of interest pixel value magnitude were each significantly associated with dose rate.

CONCLUSION - Larger patients experience higher radiation dose rates under fluoroscopy. Severely obese patients receive 3-fold higher dose rates compared with nonobese patients. Given the higher incidence of stone disease in obese patients, all attempts should be made to minimize radiation exposure during ureteroscopy.

Copyright © 2013 Elsevier Inc. All rights reserved.

MeSH Terms (16)

Adult Aged Aged, 80 and over Body Mass Index Female Fluoroscopy Humans Male Middle Aged Obesity Prospective Studies Radiation Dosage Severity of Illness Index Tomography, X-Ray Computed Ureteroscopy Young Adult

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