The innate immunity adaptor SARM translocates to the nucleus to stabilize lamins and prevent DNA fragmentation in response to pro-apoptotic signaling.

Sethman CR, Hawiger J
PLoS One. 2013 8 (7): e70994

PMID: 23923041 · PMCID: PMC3726548 · DOI:10.1371/journal.pone.0070994

MeSH Terms (17)

Apoptosis Armadillo Domain Proteins Caspase 6 Cell Line Cell Nucleus Cytoskeletal Proteins DNA Fragmentation Gene Expression Gene Order Genetic Vectors Humans Immunity, Innate Lamins Protein Stability Protein Transport Signal Transduction Tumor Necrosis Factor-alpha

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