JAM-A associates with ZO-2, afadin, and PDZ-GEF1 to activate Rap2c and regulate epithelial barrier function.

Monteiro AC, Sumagin R, Rankin CR, Leoni G, Mina MJ, Reiter DM, Stehle T, Dermody TS, Schaefer SA, Hall RA, Nusrat A, Parkos CA
Mol Biol Cell. 2013 24 (18): 2849-60

PMID: 23885123 · PMCID: PMC3771947 · DOI:10.1091/mbc.E13-06-0298

MeSH Terms (25)

Animals Capsid Proteins Cell Adhesion Molecules Cell Line Cell Membrane Permeability Cell Polarity Cytoskeleton Down-Regulation Endocytosis Epithelial Cells Guanine Nucleotide Exchange Factors Humans Mice Microfilament Proteins Models, Biological Molecular Weight Nerve Tissue Proteins Protein Binding Protein Transport rap1 GTP-Binding Proteins ras Proteins Receptors, Cell Surface rhoA GTP-Binding Protein Tight Junctions Zonula Occludens-2 Protein

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