Wolbachia: Can we save lives with a great pandemic?

LePage D, Bordenstein SR
Trends Parasitol. 2013 29 (8): 385-93

PMID: 23845310 · PMCID: PMC3775348 · DOI:10.1016/j.pt.2013.06.003

Wolbachia pipientis is the most common bacterial infection in the animal world and wields a vast influence on invertebrate reproduction, sex determination, speciation, and behavior worldwide. These avenues of research have made seminal gains, including the latest use of Wolbachia to alter mosquito populations and a strengthened focus on using anti-Wolbachia therapies against filarial nematode infections. This work is further bolstered by a more refined knowledge of Wolbachia biology spanning mechanisms to relevance. Here we tally the most up-to-date knowledge in the field and review the immense implications that this global infection has for the basic and applied life sciences.

Copyright © 2013 Elsevier Ltd. All rights reserved.

MeSH Terms (13)

Animals Culicidae Female Filariasis Global Health Humans Insect Vectors Male Nematoda Pandemics Pest Control, Biological Reproduction Wolbachia

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