Baclofen and other GABAB receptor agents are allosteric modulators of the CXCL12 chemokine receptor CXCR4.

Guyon A, Kussrow A, Olmsted IR, Sandoz G, Bornhop DJ, Nahon JL
J Neurosci. 2013 33 (28): 11643-54

PMID: 23843532 · PMCID: PMC4299549 · DOI:10.1523/JNEUROSCI.6070-11.2013

MeSH Terms (17)

Allosteric Regulation Animals Baclofen Cell Line, Tumor Chemokine CXCL12 Female GABA-B Receptor Agonists GABA Agents HEK293 Cells Humans Male Organ Culture Techniques Protein Binding Rats Rats, Wistar Receptors, CXCR4 Xenopus laevis

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