12-lipoxygenase activity plays an important role in PAR4 and GPVI-mediated platelet reactivity.

Yeung J, Apopa PL, Vesci J, Stolla M, Rai G, Simeonov A, Jadhav A, Fernandez-Perez P, Maloney DJ, Boutaud O, Holman TR, Holinstat M
Thromb Haemost. 2013 110 (3): 569-81

PMID: 23784669 · PMCID: PMC3960303 · DOI:10.1160/TH13-01-0014

MeSH Terms (17)

12-Hydroxy-5,8,10,14-eicosatetraenoic Acid Animals Arachidonate 12-Lipoxygenase Blood Platelets Cyclooxygenase 1 Eicosanoids Flow Cytometry Humans Mice Mice, Transgenic Platelet Activation Platelet Adhesiveness Platelet Aggregation Platelet Membrane Glycoproteins Receptors, Thrombin Thrombosis Time Factors

Connections (1)

This publication is referenced by other Labnodes entities:

Links