PDX1 in ducts is not required for postnatal formation of β-cells but is necessary for their subsequent maturation.

Guo L, Inada A, Aguayo-Mazzucato C, Hollister-Lock J, Fujitani Y, Weir GC, Wright CV, Sharma A, Bonner-Weir S
Diabetes. 2013 62 (10): 3459-68

PMID: 23775765 · PMCID: PMC3781453 · DOI:10.2337/db12-1833

MeSH Terms (15)

Animals Blood Glucose Cell Growth Processes Cells, Cultured Cell Survival Diabetes Mellitus, Experimental Gene Expression Regulation, Developmental Homeodomain Proteins Insulin Insulin-Secreting Cells Insulin Secretion Maf Transcription Factors, Large Mice Mice, Transgenic Trans-Activators

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