Sox4 is a master regulator of epithelial-mesenchymal transition by controlling Ezh2 expression and epigenetic reprogramming.

Tiwari N, Tiwari VK, Waldmeier L, Balwierz PJ, Arnold P, Pachkov M, Meyer-Schaller N, Schübeler D, van Nimwegen E, Christofori G
Cancer Cell. 2013 23 (6): 768-83

PMID: 23764001 · DOI:10.1016/j.ccr.2013.04.020

MeSH Terms (20)

Animals Cell Line Cell Movement Cell Survival Enhancer of Zeste Homolog 2 Protein Epigenesis, Genetic Epithelial-Mesenchymal Transition Female Gene Expression Regulation, Neoplastic Histones Humans Mammary Neoplasms, Experimental MCF-7 Cells Methylation Mice Neoplasm Metastasis Polycomb Repressive Complex 2 Promoter Regions, Genetic SOXC Transcription Factors Transcription, Genetic

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