Enhancing the power of genetic association studies through the use of silver standard cases derived from electronic medical records.

McDavid A, Crane PK, Newton KM, Crosslin DR, McCormick W, Weston N, Ehrlich K, Hart E, Harrison R, Kukull WA, Rottscheit C, Peissig P, Stefanski E, McCarty CA, Zuvich RL, Ritchie MD, Haines JL, Denny JC, Schellenberg GD, de Andrade M, Kullo I, Li R, Mirel D, Crenshaw A, Bowen JD, Li G, Tsuang D, McCurry S, Teri L, Larson EB, Jarvik GP, Carlson CS
PLoS One. 2013 8 (6): e63481

PMID: 23762230 · PMCID: PMC3677889 · DOI:10.1371/journal.pone.0063481

MeSH Terms (15)

Aged Biomarkers Case-Control Studies Chi-Square Distribution Computer Simulation Dementia Electronic Health Records Genome-Wide Association Study Genomics Genomics Humans Models, Statistical Phenotype Polymorphism, Single Nucleotide Risk Factors

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