SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase.

Laurent G, German NJ, Saha AK, de Boer VC, Davies M, Koves TR, Dephoure N, Fischer F, Boanca G, Vaitheesvaran B, Lovitch SB, Sharpe AH, Kurland IJ, Steegborn C, Gygi SP, Muoio DM, Ruderman NB, Haigis MC
Mol Cell. 2013 50 (5): 686-98

PMID: 23746352 · PMCID: PMC3721068 · DOI:10.1016/j.molcel.2013.05.012

MeSH Terms (15)

Acetylation Adipose Tissue, White Animals Carboxy-Lyases Diet Fatty Acids Lipid Metabolism Lipids Male Mice Mice, Knockout Mitochondrial Proteins Obesity Oxidation-Reduction Sirtuins

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